Paper Key : IRJ************966
Author: Vikin P.nagrik, Abhishek S. Jaware,Naval D. Chaudhari,Tushar D. Gudade,Pranjal P.mhaske,Satish S. Palkar,Tanvi V. Bhave,Rutuja R. Hajare
Date Published: 13 Apr 2024
Abstract
Cancer immunotherapy has witnessed remarkable progress in recent years, particularly with the advent of FDA-approved checkpoint blockade modulators and CAR-T cell therapies. However, the potential of cancer vaccines, particularly mRNA vaccines, remains underexplored. This review paper delves into the landscape of cancer immunotherapy, focusing on the transformative role of mRNA vaccines in targeting tumor-associated antigens. From enhancing mRNA translation stability to navigating regulatory challenges, this paper navigates through the intricate terrain of mRNA-based cancer immunotherapy, shedding light on its promises and challenges.