Paper Key : IRJ************477
Author: Mahesh Ramesh Pawar
Date Published: 07 Apr 2024
Abstract
study or experiment involving the simultaneous spectrophotometric determination of rifampicin, isoniazid, and pyrazinamide using a generalized version of the net analyte signal standard addition method (GNASSAM). The study utilized UV spectra of these compounds and involved preparing a standard solution containing a mixture of all analytes, followed by the addition of this solution to the sample. The concentrations of analytes were determined based on the changes in net analyte signals observed in the UV spectra. The results demonstrated the acceptable performance of GNASSAM in determining the concentrations of these antituberculosis medications in synthetic mixtures.
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